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The aim of this study is to determine whether a treatment strategy of surgery alone, i. For general information, Learn About Clinical Studies. Key exclusion criteria for all three trials include: Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Fit for all protocol defined treatments 7.
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ACPGBI Position Statements: Management of Anal Fissure and Management of Acute Severe Colitis

Overall survival OS , defined as time from randomisation to date of death from any cause 9. Estimated Study Completion Date:. Treatment, Drug, Radiotherapy, Active Monitoring. In addition, individual collaborators must not publish data concerning their participants which is directly relevant to the questions posed in the trial until the first publication of the analysis of the primary endpoint. April Studies a U. Patients who received standard CMT are randomized to 1 of 2 arms. Previous Trial Back to results Next Trial.
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Upcoming and future colorectal conferences, courses, workshops and meetings, searchable by location, specialism and audience. No Criteria Inclusion Criteria:. Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Choice of delivery technique is at the discretion of the treating clinician. To compare nivolumab following combined modality therapy CMT with observation in patients with high risk anal carcinoma with regard to severe toxicity interval. Information from the National Library of Medicine Choosing to participate in a study is an important personal decision.
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Description:Choice of delivery technique is at the discretion of the treating clinician. ACT3 Where a piecemeal local excision precludes assessment of tumour size and margin status. To compare nivolumab following combined modality therapy CMT with observation in patients with high risk anal carcinoma with regard to severe toxicity interval. Yes Studies a U. Abscess, fistula and fissures IBD and other colitides. Immunocompromised organ transplant Trial-specific exclusion criteria: Colostomy-free survival CFS , measured at baseline, prior to the start of treatment and throughout follow-up and will look at patients who have a pre-treatment colostomy that is still present at 12 months post end of treatment, patients who have a colostomy fitted due to a treatment related toxicity or local disease failure 7.

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